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  • The structural biochemistry of the superoxide dismutases

    2021-7-24u2002·u20023. Cu,ZnSOD. In 1938, Mann and Keilin [] isolated a bovine erythrocyte protein with a blue color contributed by bound copper.They termed the ~31.5 kDa protein hemocuprein. In the 1950s, human homologues of erythrocuprein were isolated from erythrocytes [70,71] and perhaps more pertinent to ALS, cerebrocuprein from the brain [].In 1969, 30 years after the initial isolation, McCord and Fridovich ...

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  • Evaluation of antioxidant and immunity-enhancing ...

    The effect of Sargassum pallidum (brown seaweed) aqueous extract on the immunity function and antioxidant activities in was studied gastric cancer rats. Treatment with Sargassum pallidum aqueous extract at oral doses 400, 600 or 800 mg/kg body weight was found to …

    Get Price
  • Superoxide Dismutase Activity, Hydrogen Peroxide Steady ...

    2015-9-23u2002·u2002Hydrogen peroxide steady-state concentration ([H 2 O 2]ss) in nonstimulated neutrophils did not differ among treatments at all evaluated times, with an average value of 0.08 nmol/10 7 cells. The stimulation of polymorph nuclear cells from the +Cu animals with M. bovis produced a marked increase of [H 2 O 2]ss in the suspension medium up to 0.8 ± 0.07 nmol/10 7 cells at 25 min of reaction.

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  • How To Boost The Superoxide Dismutase - Life Extension

    2 days agou2002·u2002The enzyme superoxide dismutase (SOD) is one of the body's foremost antioxidant defenses, reducing free radical damage associated with atherosclerosis, stroke, and arthritis. New bioavailable forms of SOD offer superior protection against oxygen free radicals. Scientifically reviewed by: Dr. Gary Gonzalez, MD, on January 2021.

    Get Price
  • Superoxide dismutase transgenes in sugarbeets confer ...

    Sugarbeets carrying superoxide dismutase transgenes were developed in order to investigate the possibility of enhancing their resistance to oxidative stress. Binary T-DNA vectors carrying the chloroplastic and cytosolic superoxide dismutase genes from tomato, were used for Agrobacterium-mediated transformation of sugarbeet petioles.

    Get Price
  • Superoxide Dismutase (SOD) - iHerb

    Superoxide dismutase (SOD) is an important element of the system that fights free radicals. It is thought to kill harmful bacteria and boost the immune system, however, certain other antioxidants many be better absorbed in the body and therefore provide more protection from free radical damage.

    Get Price
  • Superoxide Dismutase Assay Kit

    BioAssay Systems' Superoxide Dismutase Assay Kit (ESOD-100) provides a convenient colorimetric means for the quantitative determination of SOD enzyme activity in biological samples. Color intensity (OD440nm) is used to determine SOD activity. Linear detection range: 0.05 - 3 U/mL SOD.

    Get Price
  • Anti-SOD Antibody Products

    2021-10-29u2002·u2002Anti-SOD Antibody Products. Anti-SOD antibodies are readily available from several suppliers. SOD is a reported synonym of the human protein 'superoxide dismutase 1', encoded by the gene SOD1. The full protein is reported to be 154 amino acid residues in length. It is listed to be a member of the Cu-Zn superoxide dismutase family.

    Get Price
  • The structural biochemistry of the superoxide dismutases

    2021-7-24u2002·u20023. Cu,ZnSOD. In 1938, Mann and Keilin [] isolated a bovine erythrocyte protein with a blue color contributed by bound copper.They termed the ~31.5 kDa protein hemocuprein. In the 1950s, human homologues of erythrocuprein were isolated from erythrocytes [70,71] and perhaps more pertinent to ALS, cerebrocuprein from the brain [].In 1969, 30 years after the initial …

    Get Price
  • Evaluation of antioxidant and immunity-enhancing ...

    The effect of Sargassum pallidum (brown seaweed) aqueous extract on the immunity function and antioxidant activities in was studied gastric cancer rats. Treatment with Sargassum pallidum aqueous extract at oral doses 400, 600 or 800 mg/kg body weight was found to provide a dose-dependent protection …

    Get Price
  • Superoxide Dismutase Activity, Hydrogen Peroxide Steady ...

    2015-9-23u2002·u2002Hydrogen peroxide steady-state concentration ([H 2 O 2]ss) in nonstimulated neutrophils did not differ among treatments at all evaluated times, with an average value of 0.08 nmol/10 7 cells. The stimulation of polymorph nuclear cells from the +Cu animals with M. bovis produced a marked increase of [H 2 O 2]ss in the suspension medium up to 0.8 ± 0.07 nmol/10 7 …

    Get Price
  • Frontiers

    2021-2-25u2002·u2002Superoxide dismutase 3 (SOD3), a well-known antioxidant has been shown to possess immunomodulatory properties through inhibition of T cell differentiation. However, the underlying inhibitory mechanism of SOD3 on T cell differentiation is not well understood. In this study, we investigated the effect of SOD3 on anti-CD3/CD28- or phorbol myristate acetate (PMA) and …

    Get Price
  • How To Boost The Superoxide Dismutase - Life Extension

    2 days agou2002·u2002The enzyme superoxide dismutase (SOD) is one of the body's foremost antioxidant defenses, reducing free radical damage associated with atherosclerosis, stroke, and arthritis. New bioavailable forms of SOD offer superior protection against oxygen free radicals. Scientifically reviewed by: Dr. Gary Gonzalez, MD, on January 2021.

    Get Price
  • Superoxide dismutase transgenes in sugarbeets confer ...

    Sugarbeets carrying superoxide dismutase transgenes were developed in order to investigate the possibility of enhancing their resistance to oxidative stress. Binary T-DNA vectors carrying the chloroplastic and cytosolic superoxide dismutase genes from tomato, were used for Agrobacterium-mediated transformation of sugarbeet petioles.

    Get Price
  • Superoxide Dismutase (SOD) - iHerb

    Superoxide dismutase (SOD) is an important element of the system that fights free radicals. It is thought to kill harmful bacteria and boost the immune system, however, certain other antioxidants many be better absorbed in the body and therefore provide more protection from …

    Get Price
  • Superoxide Dismutase Assay Kit

    BioAssay Systems' Superoxide Dismutase Assay Kit (ESOD-100) provides a convenient colorimetric means for the quantitative determination of SOD enzyme activity in biological samples. Color intensity (OD440nm) is used to determine SOD activity. Linear detection range: 0.05 - 3 U/mL SOD.

    Get Price
  • Anti-SOD Antibody Products

    2021-10-29u2002·u2002Anti-SOD Antibody Products. Anti-SOD antibodies are readily available from several suppliers. SOD is a reported synonym of the human protein 'superoxide dismutase 1', encoded by the gene SOD1. The full protein is reported to be 154 amino acid residues in length. It is listed to be a member of the Cu-Zn superoxide dismutase family.

    Get Price
  • Oxidative stress and antioxidant status in dairy cows ...

    2015-7-9u2002·u2002Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods Jana Konvičná 1, Mária Vargová, Iveta Paulíková, Gabriel Kováč, Zuzana Kostecká2 University of Veterinary Medicine and Pharmacy, 1Clinic of Ruminants, 2Department of Chemistry, Biochemistry and Biophysics, Košice, Slovak Republic

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  • A new recombinant MS-superoxide dismutase alleviates 5 ...

    2019-9-10u2002·u2002Superoxide dismutase (SOD) is a potential therapy for mucositis but efficient product is not available because the enzyme is degraded following oral administration or induces an immune reaction ...

    Get Price
  • Superoxide Dismutase (SOD) - iHerb

    Superoxide dismutase (SOD) is an important element of the system that fights free radicals. It is thought to kill harmful bacteria and boost the immune system, however, certain other antioxidants many be better absorbed in the body and therefore provide more protection from free radical damage.

    Get Price
  • (PDF) Fc-Receptor-Mediated Intracellular Delivery of Cu/Zn ...

    Using specific antibodies against bovine Cu/Zn-superoxide dismutase (EC 1.15.1.1, SOD1) we demonstrated that anti-SOD antibodies (IgG1) are able to promote the intracellular translocation of the ...

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  • Rat SOD3(Extracellular superoxide dismutase [Cu-Zn])

    Product Name Rat SOD3(Extracellular superoxide dismutase [Cu-Zn]) ELISA Kit Catalogue No. ER0649 Alias SOD3 ELISA Kit, EC-SOD ELISA Kit, superoxide dismutase 3 ELISA Kit, extracellular ELISA Kit Detection Method Sandwich ELISA, Double Antibody

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  • Toxicology Research

    Oxidative stress and immune inflammatory level assay in peripheral blood Blood samples were collected from the orbit venous plexus approximately 24 h after the last treatment. The cell classification count in the blood samples was detected with an automatic blood biochemical analyzer (TBA-120 FR, Toshiba). In …

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  • Enhancing the Skin's Natural Antioxidant Enzyme System

    2009-1-1u2002·u2002Examples of endogenous, enzymatic antioxidants include: superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). SOD's role in maintaining the oxidant-antioxidant balance in the body, thus protecting the body against harmful free radicals, was first determined in 1968. Since then, numerous studies into the benefits of SOD's interactions with the free radical superoxide ...

    Get Price
  • SOD: Do You Know About This Powerful Antioxidant?

    Superoxide is produced by your cells as a waste product of cell metabolism in creating energy. In this process, your cells also create another highly damaging free radical called hydrogen peroxide or hydroxyl radicals. In reaction to these 2 damaging free radicals, your body makes superoxide dismutase (SOD) to counteract them.

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  • Frontiers

    The tropical bont tick, Amblyomma variegatum, is a tick species of veterinary importance and is considered as one of major pest of ruminants in Africa and in the Caribbean. It causes direct skin lesions, transmits heartwater, and reactivates bovine dermatophilosis. Tick saliva is reported to affect overall host responses through immunomodulatory and anti-inflammatory molecules, among other ...

    Get Price
  • Effects of heat stress on antioxidant status and immune ...

    2020-8-24u2002·u2002The study was conducted to evaluate the effects of heat stress on antioxidant status, immune response, and related gene expression of lambs. Eighteen male lambs were randomly allocated into three treatment groups that were as follows: indoor temperature control group furnished with an air-conditioner (ITC), indoor temperature non-control group suffered intermittent and varying degrees of …

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  • BLACKMORES Vitamins & Supplements - Australia's #1 ...

    Manganese is an essential trace mineral that is a co-factor in many of the body's enzymes, including superoxide dismutase. Manganese can be found in hazelnuts, blackberries, pineapple, lentils, beans and whole grains. Zinc amino acid chelate (zinc 15 mg): 75 mg. Zinc is an essential trace element that plays a role in every living cell in the body.

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  • Superoxide Dismutase (SOD) - iHerb

    Superoxide dismutase (SOD) is an important element of the system that fights free radicals. It is thought to kill harmful bacteria and boost the immune system, however, certain other antioxidants many be better absorbed in the body and therefore provide more protection from …

    Get Price
  • BK channels in innate immune functions of neutrophils and ...

    2009-2-5u2002·u2002Superoxide anion was measured as described earlier, using the superoxide dismutase-inhibitable reduction of ferricytochrome c assay. 8,9 In this study, 2.5 × 10 5 cells were incubated in a total assay volume of 200 μL with either buffer control, 25 ng/mL phorbol 12-myristate 13-acetate (PMA), or 100 μg/mL opsonized zymosan, respectively ...

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  • Myocardial Protective Effect of Extracellular Superoxide ...

    2014-2-15u2002·u2002Extracellular superoxide dismutase (ecSOD) binds to heparin sulfate proteoglycans on cellular surface as a unique scavenger of superoxide anions in the extracellular space . Many studies have shown that direct gene transfer of the cDNA encoding membrane-bound human ecSOD affords transient cardio-protective effect [ 3, 5 ].

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  • Publications - glisodin sod - gliadin complex

    Effects of a cantaloupe melon extract/wheat gliadin (Glisodin) biopolymer during aortic cross-clamping. 3. Antioxidant & Aging, Scientific studies April 1, 2007. Pre-treatment with the oral melon extract/gliadin may be a therapeutic option to reduce oxidative …

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  • Enhancing the Skin's Natural Antioxidant Enzyme System by ...

    2009-1-1u2002·u2002Examples of endogenous, enzymatic antioxidants include: superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). SOD's role in maintaining the oxidant-antioxidant balance in the body, thus protecting the body against harmful free radicals, was first determined in 1968. Since then, numerous studies into the benefits of SOD's interactions with the free radical superoxide …

    Get Price
  • A new recombinant MS-superoxide dismutase alleviates 5 ...

    2019-9-10u2002·u2002Superoxide dismutase (SOD) is a potential therapy for mucositis but efficient product is not available because the enzyme is degraded following oral administration or induces an immune …

    Get Price
  • SOD3/EC-SOD Antibody (4GG11G6) (NBP1-22417): Novus

    Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme present in almost every cell in the body (3). It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase (2, 5). In general, SODs play a major role in antioxidant ...

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  • Inhibitory Effect of Nelumbo nucifera Leaf Extract on 2 ...

    2019-9-1u2002·u2002superoxide dismutase 1 (SOD-1), and nuclear factor erythroid 2-related factor 2 (Nrf2) were purchased Antioxidants 2019, 8, 329 3 of 15 from Cell Signaling Technology (Beverly, MA, USA), and -actin as internal control was purchased

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  • Frontiers

    The tropical bont tick, Amblyomma variegatum, is a tick species of veterinary importance and is considered as one of major pest of ruminants in Africa and in the Caribbean. It causes direct skin lesions, transmits heartwater, and reactivates bovine dermatophilosis. Tick saliva is reported to affect overall host responses through immunomodulatory and anti-inflammatory molecules, …

    Get Price
  • Neurodegenerative Marker Antibody Products

    Neurodegenerative Marker Antibody Products. Neurodegenerative diseases resulting from progressive loss of neuronal function is an active area of research. Alzheimer's disease, affecting over 29 million people worldwide as of 2015, implicates a causative role of amyloid beta aggregates within the brain. These are formed from the peptide ...

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  • The structural biochemistry of the superoxide dismutases

    2021-7-24u2002·u20023. Cu,ZnSOD. In 1938, Mann and Keilin [] isolated a bovine erythrocyte protein with a blue color contributed by bound copper.They termed the ~31.5 kDa protein hemocuprein. In the 1950s, human homologues of erythrocuprein were isolated from erythrocytes [70,71] and perhaps more pertinent to ALS, cerebrocuprein from the brain [].In 1969, 30 years after the initial isolation, McCord and Fridovich ...

    Get Price
  • Evaluation of antioxidant and immunity-enhancing ...

    The effect of Sargassum pallidum (brown seaweed) aqueous extract on the immunity function and antioxidant activities in was studied gastric cancer rats. Treatment with Sargassum pallidum aqueous extract at oral doses 400, 600 or 800 mg/kg body weight was found to …

    Get Price
  • Superoxide Dismutase Activity, Hydrogen Peroxide Steady ...

    2015-9-23u2002·u2002Hydrogen peroxide steady-state concentration ([H 2 O 2]ss) in nonstimulated neutrophils did not differ among treatments at all evaluated times, with an average value of 0.08 nmol/10 7 cells. The stimulation of polymorph nuclear cells from the +Cu animals with M. bovis produced a marked increase of [H 2 O 2]ss in the suspension medium up to 0.8 ± 0.07 nmol/10 7 cells at 25 min of reaction.

    Get Price
  • Frontiers

    2021-2-25u2002·u2002Superoxide dismutase 3 (SOD3), a well-known antioxidant has been shown to possess immunomodulatory properties through inhibition of T cell differentiation. However, the underlying inhibitory mechanism of SOD3 on T cell differentiation is not well understood. In this study, we investigated the effect of SOD3 on anti-CD3/CD28- or phorbol myristate acetate (PMA) and ionomycin (ION)-mediated ...

    Get Price
  • How To Boost The Superoxide Dismutase - Life Extension

    2 days agou2002·u2002The enzyme superoxide dismutase (SOD) is one of the body's foremost antioxidant defenses, reducing free radical damage associated with atherosclerosis, stroke, and arthritis. New bioavailable forms of SOD offer superior protection against oxygen free radicals. Scientifically reviewed by: Dr. Gary Gonzalez, MD, on January 2021.

    Get Price
  • Superoxide dismutase transgenes in sugarbeets confer ...

    Sugarbeets carrying superoxide dismutase transgenes were developed in order to investigate the possibility of enhancing their resistance to oxidative stress. Binary T-DNA vectors carrying the chloroplastic and cytosolic superoxide dismutase genes from tomato, were used for Agrobacterium-mediated transformation of sugarbeet petioles.

    Get Price
  • Superoxide Dismutase (SOD) - iHerb

    Superoxide dismutase (SOD) is an important element of the system that fights free radicals. It is thought to kill harmful bacteria and boost the immune system, however, certain other antioxidants many be better absorbed in the body and therefore provide more protection from free radical damage.

    Get Price
  • Superoxide Dismutase Assay Kit

    BioAssay Systems' Superoxide Dismutase Assay Kit (ESOD-100) provides a convenient colorimetric means for the quantitative determination of SOD enzyme activity in biological samples. Color intensity (OD440nm) is used to determine SOD activity. Linear detection range: 0.05 - 3 U/mL SOD.

    Get Price
  • Anti-SOD Antibody Products

    2021-10-29u2002·u2002Anti-SOD Antibody Products. Anti-SOD antibodies are readily available from several suppliers. SOD is a reported synonym of the human protein 'superoxide dismutase 1', encoded by the gene SOD1. The full protein is reported to be 154 amino acid residues in length. It is listed to be a member of the Cu-Zn superoxide dismutase family.

    Get Price
  • Oxidative stress and antioxidant status in dairy cows ...

    2015-7-9u2002·u2002Oxidative stress and antioxidant status in dairy cows during prepartal and postpartal periods Jana Konvičná 1, Mária Vargová, Iveta Paulíková, Gabriel Kováč, Zuzana Kostecká2 University of Veterinary Medicine and Pharmacy, 1Clinic of Ruminants, 2Department of Chemistry, Biochemistry and Biophysics, Košice, Slovak Republic

    Get Price
  • Up-Regulation of Superoxide Dismutase 2 in 3D Spheroid ...

    Superoxide dismutase activity was measured using the superoxide dismutase assay kit, according to the manufacturer's instructions (Sigma). SOD2 activity was measured in the presence of a copper/zinc superoxide dismutase inhibitor (Cu/Zn SOD). Data were normalized to protein content. Absorbance values were measured at 450 nm.

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  • Superoxide Dismutase Assay Kit 7500-100-K: R&D Systems

    The assay is free of interference by other catalytic activities, and is ideal for assaying SOD in mammalian cell lysates. The kit contains the proper lysis buffer and the reagents needed for 100 experimental tests, 50 positive controls, and 50 negative controls. Unlike some other assay kits for SOD, this system is not greatly disturbed by trace ...

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  • Antioxidant enzyme activities in hepatic tissue from ...

    Superoxide dismutase activity in children with chronic liver diseases. J Hepatol 2000;32:188-92. 10. Abd Ellah MR, Niishimori K, Goryo M, Okada K, Yasuda J. Glutathione peroxidase and glucose-6-phosphate dehydrogenase activities in bovine blood and liver. J Vet Med Sci 2004;66:1219-21. 11.

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  • Iron overloaded polarizes macrophage to proinflammation ...

    tioxidant enzymes (eg, superoxide dismutase and catalase).5 ROS physiologically regulates the synthesize of some kinds of proteins, such as phosphatase and tensin homologue, epi-dermal growth factor receptor, protein kinase B, and histone deacetylases,6-9 and oxidizes DNA to promote transcription.4

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  • A chemokine-degrading extracellular protease made by group ...

    2008-1-3u2002·u2002Circumvention of the host innate immune response is critical for bacterial pathogens to infect and cause disease. Here we demonstrate that the group A Streptococcus (GAS; Streptococcus pyogenes) protease SpyCEP (S. pyogenes cell envelope protease) cleaves granulocyte chemotactic protein 2 (GCP-2) and growth-related oncogene alpha (GROalpha), two …

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  • DISCONTINUED no more available

    When given to patients aged 64-80 years, wolfberry increased blood levels of SOD by 48 percent and lowered dangerous blood lipid peroxides by 65 percent in only 10 days. SODzyme with GliSODin is a 100% vegetarian product using only plant sources for Superoxide Dismutase (SOD) catalysts and vegetarian capsules.

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  • Peripartal rumen-protected methionine supplementation to ...

    2016-3-9u2002·u2002Main objectives were to determine to what extent Smartamine M (SM) supplementation to a prepartal higher-energy diet could alter neutrophil (PMN) and liver tissue immunometabolic biomarkers, and whether those responses were comparable to those in cows fed a prepartal lower-energy diet (CON). Twenty-eight multiparous Holstein cows were fed CON (NEL = 1.24 Mcal/kg …

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  • Chemical composition and phagocyte immunomodulatory ...

    Madison, WI, USA), according to the manufacturer's protocol. After trans-fection, the cells were suspended in DMEM supplemented with 10% FBS at 37°C and used for [Ca2+] i measurements. Isolation of human neutrophils For isolation of human neutrophils, blood was …

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  • The anti-ageing molecule sirt1 ... - Immunity & Ageing

    2017-3-16u2002·u2002An exercise-based Cardiac Rehabilitation Programme (CRP) is established as adjuvant therapy in heart failure (HF), nevertheless it is underutilized, especially in the elderly. While the functional and hemodynamic effects of CRP are well known, its underlying molecular mechanisms have not been fully clarified. The present study aims to evaluate the effects of a well-structured …

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  • Determination of the Molecular Mechanism of Torularhodin ...

    2019-7-30u2002·u2002reagents according to the manufacturer's instructions. 2.4. Determination of Different H 2 O 2 Concentrations for Treatment. BRL cells were plated in 96-well plates at 5× 103 cells/well and incubated for 24h. Then, H 2 O 2 solutions at different concentrations (0, 100, 200, 300, 400, 500, 600, 700, 800, 900, and 1000 μmol/ml) were added ...

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