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  • Treatment with Actovegin® improves sensory nerve

    We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. Methods: A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce experimental diabetes in male Sprague-Dawley rats. Actovegin® (200 or 600 mg/kg) was ...

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  • [PDF] Treatment with Actovegin® improves sensory nerve ...

    BACKGROUND Diabetic neuropathy is one of the most severe complications of diabetes, affecting approximately one-third of diabetic patients. We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. METHODS A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce ...

    Get Price
  • Deproteinized calf blood hemoderivative

    Deproteinized hemoderivative of calf blood is a biological product for the treatment of vascular and metabolic disorders of the brain, diabetes, peripheral vascular pathologies and their consequences, as well as for the prevention and treatment of radiation sickness. It is applied orally and topically after consulting a doctor.

    Get Price
  • Treatment with Actovegin® improves sensory nerve

    2011-10-21u2002·u2002We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. METHODS: A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce experimental diabetes in …

    Get Price
  • Deproteinized hemoderivative of calf blood: what is it ...

    Deproteinized hemoderivative of calf blood is a preparation of biological origin, which is used in the complex treatment of metabolic disorders in the brain, diabetes and vascular pathologies. The basis of hemoderivat is an extract from processed tissues and blood of dairy calves.

    Get Price
  • Buy ACTOVEGIN® 200 mg/tab, 50 tabs/pack OR Injectables

    Actovegin® concentrate (in terms of dry deproteinized hemoderivative of calf blood) - 200 mg. Excipients: water for injection - 5 ml. Metabolic and vascular disorders of the brain: at the beginning of treatment 10 ml intravenously daily for two weeks, then 5-10 ml intravenously 3-4 times a week for at least 2 weeks.

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  • Corneal subbasal nerve fiber regeneration in myopic ...

    2012-7-1u2002·u2002A total of 26 myopic patients (52 eyes) underwent laser in situ keratomileusis.In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the corneal flap originated from the stump of corneal subbasal nerve fibers outside the ablation zone and extended towards the center of the cornea in all patients. Meanwhile, new fibers were also found to directly ...

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  • (PDF) Current Synthesis and Systematic Review of Main ...

    2020-4-30u2002·u2002PDF Background: Stroke is one of the largest problems and clinical-social challenges within neurology and, in general, pathology. Here, we briefly... Find, read and cite all the research you ...

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  • WE CHOOSE CHEAPER AND (OR) QUALITY ANALOGUES

    calf deproteinized hemoderivative - 200 mg: 50: Transparent solution with a yellow tint in ampoules of 2, 5 and 10 ml: deproteinized hemoderivative of calf blood - 80, 200 or 400 mg: 5, 10 or 25: Solution for infusion in a bottle of 250 ml: deproteinized hemoderivative of calf blood - 1000 mg: 1

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  • Treatment with Actovegin® improves sensory nerve

    We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. Methods: A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce experimental diabetes in male Sprague-Dawley rats. Actovegin® (200 or 600 mg/kg) was ...

    Get Price
  • [PDF] Treatment with Actovegin® improves sensory nerve ...

    BACKGROUND Diabetic neuropathy is one of the most severe complications of diabetes, affecting approximately one-third of diabetic patients. We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. METHODS A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce ...

    Get Price
  • Deproteinized calf blood hemoderivative

    Deproteinized hemoderivative of calf blood is a biological product for the treatment of vascular and metabolic disorders of the brain, diabetes, peripheral vascular pathologies and their consequences, as well as for the prevention and treatment of radiation sickness. It is applied orally and topically after consulting a doctor.

    Get Price
  • Treatment with Actovegin® improves sensory nerve

    2011-10-21u2002·u2002We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. METHODS: A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce experimental diabetes in …

    Get Price
  • Deproteinized hemoderivative of calf blood: what is it ...

    Deproteinized hemoderivative of calf blood is a preparation of biological origin, which is used in the complex treatment of metabolic disorders in the brain, diabetes and vascular pathologies. The basis of hemoderivat is an extract from processed tissues and blood of dairy calves.

    Get Price
  • Buy ACTOVEGIN® 200 mg/tab, 50 tabs/pack OR Injectables

    Actovegin® concentrate (in terms of dry deproteinized hemoderivative of calf blood) - 200 mg. Excipients: water for injection - 5 ml. Metabolic and vascular disorders of the brain: at the beginning of treatment 10 ml intravenously daily for two weeks, then 5-10 ml intravenously 3-4 times a week for at least 2 weeks.

    Get Price
  • Corneal subbasal nerve fiber regeneration in myopic ...

    2012-7-1u2002·u2002A total of 26 myopic patients (52 eyes) underwent laser in situ keratomileusis.In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the corneal flap originated from the stump of corneal subbasal nerve fibers outside the ablation zone and extended towards the center of the cornea in all patients. Meanwhile, new fibers were also found to directly ...

    Get Price
  • (PDF) Current Synthesis and Systematic Review of Main ...

    2020-4-30u2002·u2002PDF Background: Stroke is one of the largest problems and clinical-social challenges within neurology and, in general, pathology. Here, we briefly... Find, read and cite all the research you ...

    Get Price
  • WE CHOOSE CHEAPER AND (OR) QUALITY ANALOGUES

    calf deproteinized hemoderivative - 200 mg: 50: Transparent solution with a yellow tint in ampoules of 2, 5 and 10 ml: deproteinized hemoderivative of calf blood - 80, 200 or 400 mg: 5, 10 or 25: Solution for infusion in a bottle of 250 ml: deproteinized hemoderivative of calf blood - 1000 mg: 1

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  • Treatment of Symptomatic Polyneuropathy with

    2009-5-22u2002·u2002Actovegin® is a deproteinized hemoderivative produced from calf blood by ultrafiltration that contains low molecular weight compounds of up to 5000 Dalton. Oxygen absorption, oxygen utilization, and cellular energy metabolism are stimulated by Actovegin (9). Furthermore, Actovegin exerts insulin-like activity, such as stimulation of glucose

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  • Actovegin 40 mg ml 10 ml 5 pcs.

    Composition. 1 ampoule contains: active substance: Actovegin® concentrate (in terms of dry deproteinized hemoderivative of calf blood) 1) - 400.0 mg; excipient: water for injection - up to 10 ml. 1) The Actovegin® concentrate contains sodium chloride in the form of sodium and chlorine ions, which are components of the blood of calves.

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  • Traumatic brain injury: Current endeavours and trends

    2015-2-10u2002·u2002Actovegin is a deproteinized hemoderivative of calf blood, obtained by ultrafiltration. It contains electrolytes, essential trace elements and 30% organic components: amino acids, oligopeptides, nucleosides, inositol phospho-oligosaccharides (IPOs), intermediary products of the carbohydrate and of the lipid metabolism, and components of the

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  • Management of diabetic neuropathy - ScienceDirect

    2021-10-1u2002·u2002The amelioration of nerve dysfunction is probably related to improved blood glucose levels, although other mechanisms might be involved (lower AGE and RAGE levels in perineurium and vasa nervorum, higher C-peptide levels, reported to improve peripheral nerve function, etc.) [47,48,50,51].

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  • Comparative Analysis of the Effectiveness of Some ...

    2020-11-12u2002·u2002These include collagen (Collost ®; which contains native unreconstructed collagen obtained from the skin of cattle), 15–19 deproteinized calf blood hemoderivative (DCBH; Actovegin ®), 20–22 and mesenchymal stem cells (SCs). 23–28 An obvious advantage of the injectable drugs is the ability to accurately administer a certain volume and ...

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  • Scientific Publications - NEUROFIT Preclinical Contract ...

    NEUROFIT is a preclinical Contract Research Organization specialising in the evaluation of treatments for central and peripheral nervous system disorders. We offer a comprehensive list of in vitro and in vivo models covering a wide range of indications. NEUROFIT aims to facilitate your preclinical drug development by proposing the best models for your needs.

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  • Effect of lacrimal plugs combined with deproteinized calf ...

    2011-12-17u2002·u2002This study aims to investigate the efficacy of lacrimal plugs combined with deproteinized calf blood extract eye gel on the treatment of dry-eye-associated filamentary keratitis. Lacrimal plugs were inserted into both the upper and lower puncta of 15 patients (28 eyes). Deproteinized calf blood cxtract eye gel was applied in two patients who were not cured after this operation. All patients ...

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  • Rating of the best pills for varicose veins

    It varies from 1 month to 4 months. The main component in the composition is deproteinized hemoderivative of calf blood. With its help, stimulation of the process of work of the whole organism begins. It is able to reduce cell starvation and improve microcirculation, thereby improving blood …

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  • Treatment with Actovegin® improves sensory nerve

    We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. Methods: A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce experimental diabetes in male Sprague-Dawley rats. Actovegin® (200 or 600 mg/kg) was ...

    Get Price
  • [PDF] Treatment with Actovegin® improves sensory nerve ...

    BACKGROUND Diabetic neuropathy is one of the most severe complications of diabetes, affecting approximately one-third of diabetic patients. We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. METHODS A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce ...

    Get Price
  • Deproteinized calf blood hemoderivative

    Deproteinized hemoderivative of calf blood is a biological product for the treatment of vascular and metabolic disorders of the brain, diabetes, peripheral vascular pathologies and their consequences, as well as for the prevention and treatment of radiation sickness. It is applied orally and topically after consulting a doctor.

    Get Price
  • Treatment with Actovegin® improves sensory nerve

    2011-10-21u2002·u2002We investigated the potential neuroprotective effect of Actovegin®, a deproteinized hemoderivative of calf blood, in an animal model of diabetic neuropathy. METHODS: A single intravenous injection of streptozotocin (STZ, 55 mg/kg) was used to induce experimental diabetes in …

    Get Price
  • Deproteinized hemoderivative of calf blood: what is it ...

    Deproteinized hemoderivative of calf blood is a preparation of biological origin, which is used in the complex treatment of metabolic disorders in the brain, diabetes and vascular pathologies. The basis of hemoderivat is an extract from processed tissues and blood of dairy calves.

    Get Price
  • Buy ACTOVEGIN® 200 mg/tab, 50 tabs/pack OR Injectables

    Actovegin® concentrate (in terms of dry deproteinized hemoderivative of calf blood) - 200 mg. Excipients: water for injection - 5 ml. Metabolic and vascular disorders of the brain: at the beginning of treatment 10 ml intravenously daily for two weeks, then 5-10 ml intravenously 3-4 times a week for at least 2 weeks.

    Get Price
  • Corneal subbasal nerve fiber regeneration in myopic ...

    2012-7-1u2002·u2002A total of 26 myopic patients (52 eyes) underwent laser in situ keratomileusis.In vivo confocal microscopy revealed that most of the regenerated corneal subbasal nerve fibers in the corneal flap originated from the stump of corneal subbasal nerve fibers outside the ablation zone and extended towards the center of the cornea in all patients. Meanwhile, new fibers were also found to directly ...

    Get Price
  • (PDF) Current Synthesis and Systematic Review of Main ...

    2020-4-30u2002·u2002PDF Background: Stroke is one of the largest problems and clinical-social challenges within neurology and, in general, pathology. Here, we briefly... Find, read and cite all the research you ...

    Get Price
  • WE CHOOSE CHEAPER AND (OR) QUALITY ANALOGUES

    calf deproteinized hemoderivative - 200 mg: 50: Transparent solution with a yellow tint in ampoules of 2, 5 and 10 ml: deproteinized hemoderivative of calf blood - 80, 200 or 400 mg: 5, 10 or 25: Solution for infusion in a bottle of 250 ml: deproteinized hemoderivative of calf blood - 1000 mg: 1

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  • Features of the use of deproteinized hemoderivative blood ...

    2019. Deproteinized hemoderivative of calf blood is a biological product for the treatment of vascular and metabolic disorders of the brain, diabetes, peripheral vascular pathologies and their consequences, as well as for the prevention and treatment of radiation sickness. It is administered orally and topically after consulting a doctor.

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  • Treatment of Symptomatic Polyneuropathy With

    Treatment consisted of 20 once-daily intravenous infusions (actovegin 20% with 8 mg/ml or placebo in 250 ml sodium chloride 0.9%; infusion rate: 2 ml/min) for 20–36 days, followed by three tablets (200 mg actovegin per coated tablet or placebo) three times daily for 140 days, with a …

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  • AASCIT - Journal - HTML

    Actovegin is a deproteinized hemoderivative produced from calf blood by ultrafiltration which contains more than 200 low–molecular weight compounds of up to 5,000 Da with pleiotropic biological actions . A more detailed composition of Actovegin was given by Gulevsky et al in the 2011 study on cord blood and Actovegin in ulcer healing . By ...

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  • Advances in neurometabolic therapy

    Actovegin is a calf blood extract that contains more than 200 biologically active compounds. Experiments have shown that Actovegin reduces the neurotoxic effect of amyloid, neutralizes reactive oxygen species, and normalizes the endothelial function of small vessels. The drug has not been shown to stimulate tumor growth in the neuroblastoma model.

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  • Acta Medica Okayama - CORE

    2016-8-5u2002·u2002use of a deproteinized calf-blood extract in the treatment of disorders of the peripheral blood circulation, more particularly of the ulcerations that accompany them. This deproteinized calf-blood extract is marketed under the brand name Solcoseryl. The biological action of Solcoseryl consists in improving …

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  • Tahoma Clinic

    vegin infusion contained 40 ml deproteinized hemodialysate (dry weight 2 g) from calf-blood. EEG brain mapping, psychometric tests and evaluation of pulse, blood pressure and side effects were carried out on days I and 1 5 before as well as 2, 4, 6, and 8 h after the start of the infusion as described elsewhere [Saletu at al., 1991].

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  • Actovegin: instructions for use - tostpost.com

    2018-5-27u2002·u2002Its active substance is deproteinized gemoderivat which is prepared from calf's blood. In this low-molecular peptides and derivates of nucleic acids. To enhance the utilization inside the cells, to increase energy resource them to accelerate cellular metabolism results in the drug 'Actovegin'.

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    diabetes which system in the body ????levels. Up to 16% of adolescents with type 1 diabetes have hypertension .Twenty-four hour ambulatory BP monitoring has been used to exclude white coat hypertension and to identify loss of diurnal systolic rhythm (nondippers) with nocturnal hypertension in some normotensive adolescents with type 1 diabetes .These abnormalities may be predictive of future ...

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    Edition: {International Emergency Medicine Education Project A 75-year-old woman was brought to the emergency department (ED) by her relatives for 'not being her usual self' for a day. She was on insulin therapy for her diabetes, but otherwise healthy. On examination, she appeared confused and disoriented. Her vitals were as follow HR 95/min, RR 18/min, BP 141/85mmHg, T 37.7°C and SpO2 99 ...

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  • Predictors of response to treatment with actovegin for 6 ...

    2017-7-1u2002·u2002Actovegin, a deproteinized hemoderivative of ultrafiltered calf serum that contains low-molecular weight compounds of up to 5000 Da, 42 is approved as a drug in a number of countries. 8 The hemoderivative is a potent antihypoxic agent that stimulates the utilization of oxygen and glucose metabolism in brain cells.

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  • Advances in neurometabolic therapy

    Actovegin is a calf blood extract that contains more than 200 biologically active compounds. Experiments have shown that Actovegin reduces the neurotoxic effect of amyloid, neutralizes reactive oxygen species, and normalizes the endothelial function of small vessels. The drug has not been shown to stimulate tumor growth in the neuroblastoma model.

    Get Price
  • Actovegin solution for injection 400mg 10ml x 5 ampoules ...

    The preparation actovegin is a deproteinized hemoderivative from the blood of calves, containing only physiological substances with a molecular weight of 5000 da. The preparation Actovegin is characterized by three main effects: metabolic, neuroprotective and microcirculatory. Inositol phosphate oligosaccharides (IPO), which are part of ...

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    2016-11-10u2002·u2002Introduction: Leg ulcers are a frequent and debilitating complication of sickle cell disease (SCD), particularly of the SS genotype. The prevalence of leg ulcers in patients with sickle cell disease (SCD) varies geographically ranging widely from 75% in Jamaica to as low as 1% in Saudi Arabia. The prevalence of leg ulcers in the Cooperative Study of Sickle Cell Disease (CSSCD) in the United ...

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