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  • Superoxide Dismutase - an overview

    In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. General information. Orgotein, an enzyme (CuZn superoxide dismutase) that is present in all mammalian cells, is obtained from bovine liver by several steps, including chromatography.It can be given parenterally or topically and has been used to treat conditions such as radiation cystitis [1–7], osteoarthritis [8–11], and Peyronie ...

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a …

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002The protein amounts regularly used in our lab are as follows: For human or animal tissues and cultured cells with high SOD activity, 2, 5, 10, 15, 25, 50, 100, 200, 300 and 500 μg protein per tube.

    Get Price
  • Roles of prostaglandin F2alpha and hydrogen peroxide in ...

    2012-10-26u2002·u2002Background. Prostaglandin F 2α (PGF) from the uterus or from the ovary is responsible for the regression of the corpus luteum (CL) in mammals [1,2].In vivo studies in cows demonstrated that intramuscular injections of PGF analogues given in the mid-luteal stage induce an acute decrease in progesterone (P 4) production (functional luteolysis) followed by tissue …

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities …

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and …

    Get Price
  • Superoxide dismutase: An industrial perspective

    Superoxide dismutase (SOD) is an antioxidant enzyme protecting cells from oxidative stress. Ginger (Zingiber officinale) is known for its antioxidant properties, however, there are no data on SODs ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide. Peroxynitrite reacts relatively slowly with most biological molecules, making ...

    Get Price
  • Superoxide Dismutase - an overview

    In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. General information. Orgotein, an enzyme (CuZn superoxide dismutase) that is present in all mammalian cells, is obtained from bovine liver by several steps, including chromatography.It can be given parenterally or topically and has been used to treat conditions such as radiation cystitis [1–7], osteoarthritis [8–11], and Peyronie ...

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Roles of prostaglandin F2alpha and hydrogen peroxide in ...

    2012-10-26u2002·u2002Background. Prostaglandin F 2α (PGF) from the uterus or from the ovary is responsible for the regression of the corpus luteum (CL) in mammals [1,2].In vivo studies in cows demonstrated that intramuscular injections of PGF analogues given in the mid-luteal stage induce an acute decrease in progesterone (P 4) production (functional luteolysis) followed by tissue degradation and a decrease in ...

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002The protein amounts regularly used in our lab are as follows: For human or animal tissues and cultured cells with high SOD activity, 2, 5, 10, 15, 25, 50, 100, 200, 300 and 500 μg protein per tube.

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide ...

    Get Price
  • Superoxide dismutase: An industrial perspective

    Superoxide dismutase (SOD) is an antioxidant enzyme protecting cells from oxidative stress. Ginger (Zingiber officinale) is known for its antioxidant properties, however, there are no data on SODs ...

    Get Price
  • Frontiers

    2019-11-13u2002·u2002The localization of copper and zinc-superoxide dismutase in normal and neoplastic human skin was examined with immunochemical techniques. Skin samples were taken from males and females of different ages, UV exposed and non-exposed areas and basal-/spino-cellular carcinomas. The enzyme was localized diffusely in the cytoplasm and was also found in the nuclei of epidermal cells, endothelial ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide. Peroxynitrite reacts relatively slowly with most biological molecules, making ...

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

    Get Price
  • Superoxide Dismutase - an overview

    In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. General information. Orgotein, an enzyme (CuZn superoxide dismutase) that is present in all mammalian cells, is obtained from bovine liver by several steps, including chromatography.It can be given parenterally or topically and has been used to treat conditions such as radiation cystitis [1–7], osteoarthritis [8–11], and Peyronie ...

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Roles of prostaglandin F2alpha and hydrogen peroxide in ...

    2012-10-26u2002·u2002Background. Prostaglandin F 2α (PGF) from the uterus or from the ovary is responsible for the regression of the corpus luteum (CL) in mammals [1,2].In vivo studies in cows demonstrated that intramuscular injections of PGF analogues given in the mid-luteal stage induce an acute decrease in progesterone (P 4) production (functional luteolysis) followed by tissue degradation and a decrease in ...

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002The protein amounts regularly used in our lab are as follows: For human or animal tissues and cultured cells with high SOD activity, 2, 5, 10, 15, 25, 50, 100, 200, 300 and 500 μg protein per tube.

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide ...

    Get Price
  • Superoxide dismutase: An industrial perspective

    Superoxide dismutase (SOD) is an antioxidant enzyme protecting cells from oxidative stress. Ginger (Zingiber officinale) is known for its antioxidant properties, however, there are no data on SODs ...

    Get Price
  • Frontiers

    2019-11-13u2002·u2002The localization of copper and zinc-superoxide dismutase in normal and neoplastic human skin was examined with immunochemical techniques. Skin samples were taken from males and females of different ages, UV exposed and non-exposed areas and basal-/spino-cellular carcinomas. The enzyme was localized diffusely in the cytoplasm and was also found in the nuclei of epidermal cells, endothelial ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide. Peroxynitrite reacts relatively slowly with most biological molecules, making ...

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

    Get Price
  • Superoxide Dismutase - an overview

    In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. General information. Orgotein, an enzyme (CuZn superoxide dismutase) that is present in all mammalian cells, is obtained from bovine liver by several steps, including chromatography.It can be given parenterally or topically and has been used to treat conditions such as radiation cystitis [1–7], osteoarthritis [8–11], and Peyronie ...

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Roles of prostaglandin F2alpha and hydrogen peroxide in ...

    2012-10-26u2002·u2002Background. Prostaglandin F 2α (PGF) from the uterus or from the ovary is responsible for the regression of the corpus luteum (CL) in mammals [1,2].In vivo studies in cows demonstrated that intramuscular injections of PGF analogues given in the mid-luteal stage induce an acute decrease in progesterone (P 4) production (functional luteolysis) followed by tissue degradation and a decrease in ...

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002The protein amounts regularly used in our lab are as follows: For human or animal tissues and cultured cells with high SOD activity, 2, 5, 10, 15, 25, 50, 100, 200, 300 and 500 μg protein per tube.

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide ...

    Get Price
  • Superoxide dismutase: An industrial perspective

    Superoxide dismutase (SOD) is an antioxidant enzyme protecting cells from oxidative stress. Ginger (Zingiber officinale) is known for its antioxidant properties, however, there are no data on SODs ...

    Get Price
  • Frontiers

    2019-11-13u2002·u2002The localization of copper and zinc-superoxide dismutase in normal and neoplastic human skin was examined with immunochemical techniques. Skin samples were taken from males and females of different ages, UV exposed and non-exposed areas and basal-/spino-cellular carcinomas. The enzyme was localized diffusely in the cytoplasm and was also found in the nuclei of epidermal cells, endothelial ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide. Peroxynitrite reacts relatively slowly with most biological molecules, making ...

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

    Get Price
  • Discrete Generation of Superoxide and Hydrogen Peroxide

    2002-1-7u2002·u2002Reactive oxygen species (ROS) * are generated by all mammalian cells as by-products of metabolism or apoptotic signals and by some cells in host defense response to noxious stimuli. In general, production of ROS is associated with deleterious effects in pathophysiologic conditions, including inflammatory responses, apoptosis, or ischemia/reperfusion ().

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  • Ameliorative Effect of Fisetin on Cisplatin-Induced ...

    2014-9-3u2002·u2002Nephrotoxicity is a dose-dependent side effect of cisplatin limiting its clinical usage in the field of cancer chemotherapy. Fisetin is a bioactive flavonoid with recognized antioxidant and anti-inflammatory properties. In the present study, we investigated the potential renoprotective effect and underlying mechanism of fisetin using rat model of cisplatin-induced nephrotoxicity.

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  • Acetyl-L-Carnitine Supplementation Differently Influences ...

    Protein content was determined as described by Brooks et al., and converted to energy as protein by using the value of 23.5 kJ/g. Free triiodothyronine and leptin serum concentrations. The blood samples, collected via the inferior cava vein, were centrifuged at 2000 × g for 10 min. Serum was removed and stored at −20°C until used for ...

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  • HIF-1α/JMJD1A signaling regulates inflammation and ...

    2021-9-3u2002·u2002Endothelial cell (EC) injury accelerates the progression of diabetic macrovascular complications. Hypoxia is an important cause of EC injury. Hypoxia-inducible factor-1 alpha (HIF-1α) is an important hypoxia regulatory protein. Our previous studies showed that high-glucose and hypoxic conditions could upregulate HIF-1α expression and enhance EC inflammatory injury, independently of …

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  • Hypolipidemic activity of Dracocephalum kotschyi

    2018-10-30u2002·u2002ation of each sample, the activity of SOD (superoxide dismutase) was assayed based on inhibition of NBT re-duction to formazan [14]. One unit of SOD activity was expressed as 50% inhibition of NBT reduction per mi-nute per mg of protein. Catalase activity was determined by measuring the decomposition of H2O2 per minute per mg of protein [15].

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  • Effect of antioxidants on preimplantation embryo ...

    In vitro culture of the embryo is a useful method to treat infertility that shows embryo potential for selecting the best one to transfer and successfully implantation. However, embryo development in vitro is affected by oxidative stresses such as reactive oxygen species that may damage embryo development. Antioxidants are molecules found in fruits, vegetables, and fish that play an important ...

    Get Price
  • Oxidants and Antioxidants

    Oxidants/Antioxidants in the Liver and Lung of Individuals with Inherited Alpha-1 Antitrypsin Deficiency. Severe inherited alpha-1 antitrypsin deficiency (AATD) is a monogenic, autosomal, co-dominant, inherited disease associated with a risk for developing liver disease at any age and/or early onset emphysema.

    Get Price
  • Coordinated Changes of Mitochondrial Biogenesis and ...

    2009-1-2u2002·u2002The leaked-out electrons of electron transport chain react with oxygen to form superoxide anions (O 2 ·), which can be converted by superoxide dismutase (SOD) to hydrogen peroxide (H 2 O 2), followed by further decomposition to H 2 O and O 2 by catalase and glutathione peroxidase [12, 13]. Since ROS also serves as a second messenger in signal ...

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  • Cloning and heterologous expression of the manganese ...

    2011-3-3u2002·u2002Bacterial strains and plasmids. The bacterial strains, plasmids and primers used in this study are listed in Table 1. Escherichia coli DH5α was used for gene cloning and E. coli BL21(DE3) was used as a host for the expression of the recombinant proteins.L casei Lc18 and Lc2 and L. acidophilus LA11 and LA12 were provided by Shanghai Jiao Da Onlly Co. (Shanghai, PR China.

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  • CSIRO PUBLISHING

    RD12271Effect of superstimulatory treatments on the expression of genes related to ovulatory capacity, oocyte competence and embryo development in cattle. Ciro M. Barros, Rafael A. Satrapa, Anthony C. S. Castilho, Patrícia K. Fontes, Eduardo M. Razza, Ronaldo …

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  • Superoxide Dismutase - an overview

    In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. General information. Orgotein, an enzyme (CuZn superoxide dismutase) that is present in all mammalian cells, is obtained from bovine liver by several steps, including chromatography.It can be given parenterally or topically and has been used to treat conditions such as radiation cystitis [1–7], osteoarthritis [8–11], and Peyronie ...

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Roles of prostaglandin F2alpha and hydrogen peroxide in ...

    2012-10-26u2002·u2002Background. Prostaglandin F 2α (PGF) from the uterus or from the ovary is responsible for the regression of the corpus luteum (CL) in mammals [1,2].In vivo studies in cows demonstrated that intramuscular injections of PGF analogues given in the mid-luteal stage induce an acute decrease in progesterone (P 4) production (functional luteolysis) followed by tissue degradation and a decrease in ...

    Get Price
  • Measurement of superoxide dismutase, catalase and ...

    2009-12-17u2002·u2002The protein amounts regularly used in our lab are as follows: For human or animal tissues and cultured cells with high SOD activity, 2, 5, 10, 15, 25, 50, 100, 200, 300 and 500 μg protein per tube.

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide ...

    Get Price
  • Superoxide dismutase: An industrial perspective

    Superoxide dismutase (SOD) is an antioxidant enzyme protecting cells from oxidative stress. Ginger (Zingiber officinale) is known for its antioxidant properties, however, there are no data on SODs ...

    Get Price
  • Frontiers

    2019-11-13u2002·u2002The localization of copper and zinc-superoxide dismutase in normal and neoplastic human skin was examined with immunochemical techniques. Skin samples were taken from males and females of different ages, UV exposed and non-exposed areas and basal-/spino-cellular carcinomas. The enzyme was localized diffusely in the cytoplasm and was also found in the nuclei of epidermal cells, endothelial ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide. Peroxynitrite reacts relatively slowly with most biological molecules, making ...

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

    Get Price