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  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

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  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide.

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide ...

    Get Price
  • Dietary exposure to continuous small doses of α ...

    2014-1-1u2002·u2002Superoxide dismutase activity. Whole blood superoxide dismutase (SOD) activity was determined using a procedure modified from the original method published by and the modifications published by . Samples were prepared by diluting whole blood with H 2 O (1:20, v/v). Twenty microliter diluted sample was mixed with 20 μL chloroform/ethanol (1:2 ...

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

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  • Induction of mitochondrial manganese superoxide

    2002-4-20u2002·u2002Manganese superoxide dismutase (MnSOD) located in the mitochondrial matrix is one of the most important antioxidant enzymes protecting mitochondria against oxidative stress ( 22; 44). MnSOD, induced by ROS ( 43 ), dismutates superoxide to hydrogen peroxide, which can then be scavenged by catalase and glutathione peroxidases.

    Get Price
  • Frontiers

    2019-4-16u2002·u2002The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for 4 weeks that either remained unadulterated [EVs and RNA-sufficient (ERS; n = 12)] or was sonicated [EVs and RNA-depleted (ERD; n = 12)].

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a …

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities …

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide.

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide …

    Get Price
  • Dietary exposure to continuous small doses of α ...

    2014-1-1u2002·u2002Superoxide dismutase activity. Whole blood superoxide dismutase (SOD) activity was determined using a procedure modified from the original method published by and the modifications published by . Samples were prepared by diluting whole blood with H 2 O (1:20, v/v). Twenty microliter diluted sample was mixed with 20 μL chloroform/ethanol (1:2 ...

    Get Price
  • Frontiers

    2019-11-13u2002·u2002The localization of copper and zinc-superoxide dismutase in normal and neoplastic human skin was examined with immunochemical techniques. Skin samples were taken from males and females of different ages, UV exposed and non-exposed areas and basal-/spino-cellular carcinomas. The enzyme was localized diffusely in the cytoplasm and was also found in the …

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

    Get Price
  • Induction of mitochondrial manganese superoxide dismutase ...

    2002-4-20u2002·u2002Manganese superoxide dismutase (MnSOD) located in the mitochondrial matrix is one of the most important antioxidant enzymes protecting mitochondria against oxidative stress ( 22; 44). MnSOD, induced by ROS ( 43 ), dismutates superoxide to hydrogen peroxide, which can then be scavenged by catalase and glutathione peroxidases.

    Get Price
  • Frontiers

    2019-4-16u2002·u2002The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for 4 weeks that either remained unadulterated [EVs and RNA-sufficient (ERS; n = 12)] or was sonicated [EVs and RNA-depleted …

    Get Price
  • Amazon.com: Biotics Research Cytozyme Orchic Contains raw ...

    Orchic Concentrate (bovine), Superoxide Dismutase (from vegetable culture†), Catalase (from vegetable culture†) † Specially grown, biologically active vegetable culture containing naturally associated phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

    Get Price
  • Identification of biomarkers for the antiangiogenic and ...

    2008-2-5u2002·u2002Superoxide dismutase 3 activity in human plasma is low, but increases upon treatment with heparin (Tasaki et al, 2006). Blood from laboratory personnel who had volunteered for …

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  • Effect of dietary bovine lactoferin on performance and ...

    Superoxide dismutase, which is the main parameter to assess oxidative status [38], catalyzes the dismutation of the superoxide radical anion [39]. Bovine milk contains Cu-Zn superoxide dismutase ...

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  • Glucose-sensing microRNA-21 disrupts ROS homeostasis

    2018-7-23u2002·u2002Antioxidant enzymes play a fundamental role in counteracting oxidative stress induced by high glucose. Although mitochondrial superoxide dismutase (SOD2) is the principal defence against the toxicity of superoxide anions, the mechanism of its inactivation in diabetic subjects is still poorly understood. Recently, microRNA-21 has been associated with diabetes, although its function remains …

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  • Acetyl-L-Carnitine Supplementation Differently Influences ...

    Fat content was determined by the method of Folch et al., and converted to energy as fat by using the coefficient of 39.2 kJ/g. Protein content was determined as described by Brooks et al., and converted to energy as protein by using the value of 23.5 kJ/g. Free triiodothyronine and leptin serum concentrations.

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  • Defense of the Bovine Mammary Gland by

    The primary phagocytic cells of the bovine mammary gland, polymorphonuclear neutrophil leukocytes (PMN), and macrophages, comprise the first line of defense against invading pathogens. In the normal healthy mammary gland, macrophages predominate and act as sentinels to invading mastitis-causing pathogens. Once invaders are detected, macrophages, and possibly mammary epithelial cells, release ...

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  • Antioxidants and antioxidant methods: an updated

    2020-3-16u2002·u2002Antioxidants had a growing interest owing to their protective roles in food and pharmaceutical products against oxidative deterioration and in the body and against oxidative stress-mediated pathological processes. Screening of antioxidant properties of plants and plant-derived compounds requires appropriate methods, which address the mechanism of antioxidant activity and focus on the …

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  • Immunomodulatory and Antioxidative potentials of

    2020-10-6u2002·u2002Adipose-derived stem cells (ASCs) are considered ideal candidates for both research and cellular therapy due to ease of access, large yield, feasibility, and efficacy in preclinical and clinical studies. Unlike the subcutaneous abdominal fat depot, breast ASCs features are still not well recognized, limiting their possible therapeutic use. ASCs were found to exert immunomodulatory and ...

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  • Tea polyphenols alleviate high fat and high glucose ...

    2014-3-2u2002·u2002Background Hyperglycemia-induced endothelial hyperpermeability is crucial to cardiovascular disorders and macro-vascular complications in diabetes mellitus. The objective of this study is to investigate the effects of green tea polyphenols (GTPs) on endothelial hyperpermeability and the role of nicotinamide adenine dinucleotide phosphate (NADPH) pathway. Methods Male Wistar rats fed on a …

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  • Amazon.com: Biotics Research Cytozyme Orchic Contains

    Orchic Concentrate (bovine), Superoxide Dismutase (from vegetable culture†), Catalase (from vegetable culture†) † Specially grown, biologically active vegetable culture containing naturally associated phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

    Get Price
  • Pine Pollen Testosterone - 5 ways this herb jacks up your ...

    2018-6-21u2002·u2002Pine Pollen Effects & Benefits. Pine pollen is a supplement derived from (obviously) the pollen of pine trees, usually the Masson pine, the Chinese oil pine, or the Scots Pine.. Aside from helping ED, it has wide range of benefits that will make you healthier, and more sexually fit . First, pine pollen is full of vitamins, minerals, and amino acids, which collectively work to help your body ...

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  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide.

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide ...

    Get Price
  • Dietary exposure to continuous small doses of α ...

    2014-1-1u2002·u2002Superoxide dismutase activity. Whole blood superoxide dismutase (SOD) activity was determined using a procedure modified from the original method published by and the modifications published by . Samples were prepared by diluting whole blood with H 2 O (1:20, v/v). Twenty microliter diluted sample was mixed with 20 μL chloroform/ethanol (1:2 ...

    Get Price
  • Frontiers

    2019-11-13u2002·u2002The localization of copper and zinc-superoxide dismutase in normal and neoplastic human skin was examined with immunochemical techniques. Skin samples were taken from males and females of different ages, UV exposed and non-exposed areas and basal-/spino-cellular carcinomas. The enzyme was localized diffusely in the cytoplasm and was also found in the nuclei of epidermal cells, endothelial ...

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

    Get Price
  • Induction of mitochondrial manganese superoxide

    2002-4-20u2002·u2002Manganese superoxide dismutase (MnSOD) located in the mitochondrial matrix is one of the most important antioxidant enzymes protecting mitochondria against oxidative stress ( 22; 44). MnSOD, induced by ROS ( 43 ), dismutates superoxide to hydrogen peroxide, which can then be scavenged by catalase and glutathione peroxidases.

    Get Price
  • Frontiers

    2019-4-16u2002·u2002The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for 4 weeks that either remained unadulterated [EVs and RNA-sufficient (ERS; n = 12)] or was sonicated [EVs and RNA-depleted (ERD; n = 12)].

    Get Price
  • Amazon.com: Biotics Research Cytozyme Orchic Contains

    Orchic Concentrate (bovine), Superoxide Dismutase (from vegetable culture†), Catalase (from vegetable culture†) † Specially grown, biologically active vegetable culture containing naturally associated phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-). Nitric oxide is the only biological molecule produced in high enough concentrations to out-compete superoxide dismutase for superoxide.

    Get Price
  • The expression of sirtuins, superoxide dismutase, and ...

    2019-2-8u2002·u2002Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabetes (T2D), and HT on the expression levels of SIRT1, SIRT3, and manganese superoxide ...

    Get Price
  • Dietary exposure to continuous small doses of α ...

    2014-1-1u2002·u2002Superoxide dismutase activity. Whole blood superoxide dismutase (SOD) activity was determined using a procedure modified from the original method published by and the modifications published by . Samples were prepared by diluting whole blood with H 2 O (1:20, v/v). Twenty microliter diluted sample was mixed with 20 μL chloroform/ethanol (1:2 ...

    Get Price
  • Frontiers

    2019-11-13u2002·u2002The localization of copper and zinc-superoxide dismutase in normal and neoplastic human skin was examined with immunochemical techniques. Skin samples were taken from males and females of different ages, UV exposed and non-exposed areas and basal-/spino-cellular carcinomas. The enzyme was localized diffusely in the cytoplasm and was also found in the nuclei of epidermal cells, endothelial ...

    Get Price
  • Home Page: Journal of Biological Chemistry

    We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.

    Get Price
  • Induction of mitochondrial manganese superoxide

    2002-4-20u2002·u2002Manganese superoxide dismutase (MnSOD) located in the mitochondrial matrix is one of the most important antioxidant enzymes protecting mitochondria against oxidative stress ( 22; 44). MnSOD, induced by ROS ( 43 ), dismutates superoxide to hydrogen peroxide, which can then be scavenged by catalase and glutathione peroxidases.

    Get Price
  • Frontiers

    2019-4-16u2002·u2002The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for 4 weeks that either remained unadulterated [EVs and RNA-sufficient (ERS; n = 12)] or was sonicated [EVs and RNA-depleted (ERD; n = 12)].

    Get Price
  • Amazon.com: Biotics Research Cytozyme Orchic Contains

    Orchic Concentrate (bovine), Superoxide Dismutase (from vegetable culture†), Catalase (from vegetable culture†) † Specially grown, biologically active vegetable culture containing naturally associated phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

    Get Price
  • Extracellular superoxide dismutase inhibits hepatocyte ...

    2017-11-10u2002·u2002We have previously shown tumor suppressive effects of extracellular superoxide dismutase, EcSOD in breast cancer cells. In this study, an RTK signaling array revealed an inhibitory effect of EcSOD on c-Met phosphorylation and its downstream kinase c-Abl in MDA-MB231 cells.

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  • Effects of different models of sucrose intake on the ...

    2021-5-18u2002·u2002The aim of the study was to assess the effect of different models of sucrose intake on carbohydrate-lipid metabolism and changes in oxidant balance in the ovaries and uterus of rats. Animals were divided into three groups: I—basic feed, II—feed contains 8% of sucrose, III—alternately every second week the basic feed and modified feed contains 16% of sucrose.

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  • Pyrroloquinoline quinone Research Breakdown

    2021-9-16u2002·u20021 Sources and Structure 1.1 Sources. Pyrroloquinoline quinone (PQQ) is a quinone molecule that was first identified as an enzymatic cofactor in bacteria, acting as a prosthetic group similar to how B-vitamins work in humans. It is doubtful that PQQ is an enzymatic cofactor in humans, although it still appears to have affinity to proteins in the human body and can bind to them to confer ...

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  • Thieme E-Journals - Planta Medica Full Text

    Chia seed and chia seed oil returned superoxide dismutase levels to normal, albeit lower than the control group . Concurrent with the work submitted by Marineli, Ferreira et al. [ 22 ] were able to demonstrate that insulin levels and insulin sensitivity were improved by a diet of chia seed.

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  • Inflammatory processes in muscle injury and repair ...

    2005-2-1u2002·u2002Modified muscle use or injury can produce a stereotypic inflammatory response in which neutrophils rapidly invade, followed by macrophages. This inflammatory response coincides with muscle repair, regeneration, and growth, which involve activation and proliferation of satellite cells, followed by their terminal differentiation. Recent investigations have begun to explore the relationship ...

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  • Amazon.com: sod supplements

    REVIVIFY Pro-Vitality Fruit Blend with Superoxide Dismutase (SOD), 1 fl oz Gel Packet, 30-Day Supply 4.0 out of 5 stars 14 100% Pure DIOSMIN Pure Ingredient no Mixes or Additives for Blood Circulation, Leg Veins Health, Purity Guarantee Best Quality 90 Capsules

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  • Inhibiting miR‐27a and miR‐142‐5p attenuate nonalcoholic ...

    2019-12-30u2002·u20021 INTRODUCTION. The increase in prevalence of obesity is one of the most important challenge of public health in the world. 1, 2 Obesity appears to be associated with the development of a complex set of factors that promote the risk of increasing cardiovascular disease, type 2 diabetes and metabolic syndrome. 2-4 The hepatic manifestation of the metabolic syndrome is nonalcoholic fatty …

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  • Pine polyphenols from Pinus koraiensis prevent injuries ...

    2021-11-1u2002·u2002Pine polyphenols (PPs) are bioactive dietary constituents that enhance health and help prevent diseases through antioxidants. Antioxidants reduce the level of oxidative damages caused by ionizing radiation (IR). The main purpose of this paper is to study the protective effect of PPs on peripheral blood, liver and spleen injuries in mice induced by IR.

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  • Antioxidant and C5a-blocking strategy for hepatic

    2021-4-15u2002·u2002Nonspecific liver uptake of nanomaterials after intravenous injection has hindered nanomedicine for clinical translation. However, nanomaterials' propensity for liver distribution might enable their use in hepatic ischemia–reperfusion injury (IRI) repair. During hepatic IRI, reactive oxygen species (ROS) are generated and the fifth component of complement (C5a) is activated.

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  • Chromium ions inactivate electron transport and enhance ...

    The peroxisomal contamination of the preparation was low with a contaminating catalase activity ranging between 15 and 20 nmol min −1 per mg protein. Plant growth and chromium content. Dry weight of roots and shoots was determined after placing samples in hot air …

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