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  • Further Characterization of Bovine Superoxide Dismutase ...

    1971-5-10u2002·u2002The superoxide dismutase from bovine erythrocytes and from bovine heart were accordingly analyzed for zinc by the dithizone method (14). The erythrocyte enzyme was found to contain 1.71 and the heart enzyme 1.76 moles of zinc per 32,600 g of enzyme.

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  • Variation of Superoxide Dismutase in Bovine Milk ...

    1978-8-1u2002·u2002Variation in the enzyme (superoxide dismutase) concentration may have a minor effect on the oxidative stability of individual cow's milk. Milk from 11 Holsteins and 11 Jerseys were analyzed for 17 wk for superoxide dismutase, xanthine oxidase, oxidized lipids as determined by thiobarbituric acid values, milk produced, and fat content.

    Get Price
  • SOD B®

    SOD B ® is a dried melon juice concentrate naturally rich in SuperOxide Dismutase (SOD), obtained from a non-GMO proprietary variety of Cantaloup melon. SOD B ® is the unique source of bioactive melon SOD worldwide. SOD represents 85 to 90% of the total antioxidant capacity of SOD B ®. As a concentrate, SOD B ® is not pure SOD and also contains secondary antioxidants such as glutathione ...

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Superoxide Dismutase - an overview

    Superoxide dismutase (SOD) is a crucial scavenging enzyme that oxidatively phosphorylates superoxide anions into hydrogen peroxides. 16 It plays an essential role in protecting cells against lipid peroxidation. 28 The antioxidant SOD is highly sensitive to any slight change in the redox state of the cell and its level rises up in response to ...

    Get Price
  • Superoxide Dismutases: Role in Redox Signaling, Vascular ...

    2011-9-15u2002·u2002Generation and metabolism of reactive oxygen species (ROS). Superoxide (O 2 •−) is produced by NADPH oxidase, xanthine oxidase, nitric oxide synthase (NOS), lipoxygenase, and mitochondrial enzymes.Superoxide is converted by superoxide dismutase (SOD) to H 2 O 2, which, in turn, is reduced to water by catalase, glutathione peroxidases (GPx), and peroxiredoxins (Prx).

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  • (PDF) Blood antioxidant profile and lipid peroxides in ...

    and SCC recorded in milk of mastitic cows were 3.67 revealed a significant decrease in GSH concentration. 5. ±0.13 and 83.12±1.17 x 10 per ml respectively. Out of in mastitic cows which may be ...

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002Nitric oxide is removed within seconds in vivo by diffusion over 100 microns through tissues to enter red blood cells and react with oxyhemoglobin. The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-).

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  • Superoxide Dismutase and Glutathione Peroxidase

    2019-10-12u2002·u2002sent study was to measure the activity of the enzymes superoxide dismutase (SOD; Enzyme Commission number [EC] 1.15.1.1) and glutathione peroxidase (SeGSHPx; EC 1.11.1.9) in human milk, to record changes in enzyme activity over time and to determine whether there are differences in activity between the milk of mothers of full-term (FT) and premature (PT) infants. Methods Nine samples were ...

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  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002Nitric oxide is removed within seconds in vivo by diffusion over 100 microns through tissues to enter red blood cells and react with oxyhemoglobin. The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-).

    Get Price
  • Regulation of Cu-Zn superoxide dismutase on SCN2A in

    2013-11-11u2002·u2002In order to evaluate SCN2A as a candidate gene for epileptic susceptibility and the use of a Cu-Zn superoxide dismutase (SOD) supplement as a potential therapy for epilepsy, SCN2A expression in the cortex and the correlation between SCN2A and Cu-Zn SOD in SH-SY5Y cells were examined. SCN2A expression and the concentration of Cu-Zn SOD in the cerebral cortexes of patients with …

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  • THERAPEUTIC ANTI-MICROBIAL OXIDATIVE RESPONSES

    2020-12-4u2002·u2002Progress 10/01/98 to 09/30/04 Outputs The intent of the proposal was to characterize the pro- and anti-oxidant responses in cows' milk with a view towards enhancing defence of the mammary gland against pathogens that cause mastitis. Cow's milk was found to contain large amounts of pro-oxidant enzymes xanthine oxidase and myeloperoxidase, as well as the anti-oxidant enzyme catalase.

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  • Wine Polyphenols Stimulate Superoxide Anion

    2004-12-8u2002·u2002decrease low-density lipoprotein oxidation and to inhibit platelet aggregation (Serafini et al. 1998, Aviram and Fuhrman 2002), to decrease blood pressure and to improve endothelial function (Duarte 2001). These et al. properties could in part explain the beneficial effect of polyphenolic compounds in certain types of cardiovascular diseases.

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  • Induction of mitochondrial manganese superoxide

    2002-4-20u2002·u2002Manganese superoxide dismutase (MnSOD) located in the mitochondrial matrix is one of the most important antioxidant enzymes protecting mitochondria against oxidative stress ( 22; 44). MnSOD, induced by ROS ( 43 ), dismutates superoxide to hydrogen peroxide, which can then be scavenged by catalase and glutathione peroxidases.

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  • REVIEW Open Access A review of fatty acid profiles and ...

    2017-8-28u2002·u2002REVIEW Open Access A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef Cynthia A Daley1*, Amber Abbott1, Patrick S Doyle1, Glenn A Nader2, Stephanie Larson2 Abstract Growing consumer interest in grass-fed beef products has raised a number of questions with regard to the per-

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  • Age-dependent changes in the expression of superoxide ...

    2006-9-27u2002·u2002Introduction. Reproductive capacity in women declines dramatically beyond the mid-30s (te Velde and Pearson, 2002).The prevailing concept of female reproductive ageing assumes that the decline of both quantity and quality of the oocyte/follicle pool determines an age-dependent loss of female fertility (Ottolenghi et al., 2004).Although the primary cause for this decline is the gradual ...

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  • Identification and Molecular Characterization of ...

    2019-9-16u2002·u2002Philasterides dicentrarchi is a free-living microaerophilic scuticociliate that can become a facultative parasite and cause a serious parasitic disease in farmed fish. Both the free-living and ...

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  • Frontiers

    2019-4-16u2002·u2002The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for 4 weeks that either remained unadulterated [EVs and RNA-sufficient (ERS; n = 12)] or was sonicated [EVs and RNA-depleted (ERD; n = 12)].

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  • Identification and Molecular Characterization of ...

    2019-9-16u2002·u2002Philasterides dicentrarchi is a free-living microaerophilic scuticociliate that can become a facultative parasite and cause a serious parasitic disease in farmed fish. Both the free-living and ...

    Get Price
  • (PDF) Microtiter plate assay for superoxide dismutase ...

    A simple microtiter plate based colorimetric assay for superoxide dismutase is described. The method, involves generation of superoxide by pyrogallol autoxidation and the inhibition of superoxide ...

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  • RESEARCH Open Access Amelioration of diet-induced ...

    2017-8-26u2002·u2002NASH [5,6]. In these patients, superoxide dismutase activity, the serum vitamin C and a-tocopherol concen-trations are low, whereas lipid peroxidation and protein carbonylation levels are high [7]. Lipid peroxidation pro-ducts initiate chemical modification of many biological molecules and also they participate in signal transduc-

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  • Hepatoprotective effects of flavonoids from common ...

    high-sugar and high-fat diets (Composition: 10% lard, 10% sucrose and 5% cholesterol) for 4 weeks with some modifications according to Zhang et al. (2008). Rats gradually showed polyphagia, polydipsia, and polyuria, with low spirits and yellow coat color. The glucose level was measured from the tail vein blood using glucose oxidase method with

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  • RESEARCH Open Access Onion peel extracts ameliorate ...

    2017-8-27u2002·u2002superoxide dismutase activity and malondialdehyde formation, plasma free fatty acids, and hepatic protein expressions of IL-6 were significantly reduced by 1% OPE administration (P = 0.0393, 0.0237, 0.0148 and 0.0025, respectively). Conclusion: OPE might improve glucose response and insulin resistance associated with type 2 diabetes by

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  • i na r y Scie Journal of Veterinary Science & Technology

    2020-3-13u2002·u2002Aebi [22]. The activity of superoxide dismutase (SOD) was measured as per the method of Madesh and Balasubramanian [23]. Glutathione peroxidase (GPx) activity was determined by the method of Paglia and Valentine [24]. The protein content was estimated by the method of lowry et al. [25] using bovine serum albumin as standard. Statistical analysis

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  • Age-dependent changes in the expression of superoxide ...

    2006-9-27u2002·u2002Introduction. Reproductive capacity in women declines dramatically beyond the mid-30s (te Velde and Pearson, 2002).The prevailing concept of female reproductive ageing assumes that the decline of both quantity and quality of the oocyte/follicle pool determines an age-dependent loss of female fertility (Ottolenghi et al., 2004).Although the primary cause for this decline is the gradual ...

    Get Price
  • Antioxidative and Hypolipidemic Effects of Diosgenin, a ...

    2018-11-11u2002·u2002Antioxidative and Hypolipidemic Effects of Diosgenin, a Steroidal Saponin of Yam (Dioscorea spp.), on High-Cholesterol Fed Rats In Suk SON,1 Ji Hyun KIM,1 Ho Yong SOHN,1 Kun Ho SON,1 Jong-Sang KIM,2 and Chong-Suk KWON1;y 1Department of Food Science and Nutrition, Andong National University, Andong 760-749, Korea 2Department of Animal Science and Biotechnology, …

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  • BLACKMORES Vitamins & Supplements - Australia's #1 ...

    Manganese is an essential trace mineral that is a co-factor in many of the body's enzymes, including superoxide dismutase. Manganese can be found in hazelnuts, blackberries, pineapple, lentils, beans and whole grains. Zinc amino acid chelate (zinc 15 mg): 75 mg. Zinc is an essential trace element that plays a role in every living cell in the body.

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  • High dietary salt decreases antioxidant defenses in the ...

    2019-6-24u2002·u2002RESEARCH ARTICLES High dietary salt decreases antioxidant defenses in the liver of fructose-fed insulin-resistant rats Waleska Claudia Dornasa, Wanderson Geraldo de Limaa,b, Rinaldo Cardoso dos Santosc, Joyce Ferreira da Costa Guerraa, Melina Oliveira de Souzaa, Maísa Silvaa, Lorena Souza e Silvaa, Mirla Fiuza Dinizb, Marcelo Eustáquio Silvaa,c,⁎ aResearch in Biological …

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  • Identification and Molecular Characterization of ...

    2019-9-16u2002·u2002Philasterides dicentrarchi is a free-living microaerophilic scuticociliate that can become a facultative parasite and cause a serious parasitic disease in farmed fish. Both the free-living and ...

    Get Price
  • Investigation of the antioxidant defensive role of both

    Superoxide dismutase (SOD) according to Nishikimi et al. (1972), Glutathione (GSH) according to Prins and Loose (1969), Heme-oxygenase 1 (HO-1) according to Gonen and Rubenstein (1978) and Total antioxidant capacity (TAC) according to Koracevic et al. (2001)], all according to the instructions of the supplier. Meanwhile, tissue G0/G1% in

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  • Mammary gene expression and activity of antioxidant ...

    The effects of flax meal (FM) on the activity of antioxidant enzymes (superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT)) in the blood, mammary tissue and ruminal fluid, and oxidative stress indicators (thiobarbituric acid-reactive substances (TBARS) and 1,1-diphenyl-2-picrylhydrazyl-scavenging activity) in the milk, plasma and ruminal fluid of dairy cows were determined.

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  • Liposomal recombinant human superoxide-dismutase for

    What is claimed is: 1. A method for the prophylactic or therapeutic intervention of a pathological condition affecting a human body or part thereof, wherein said condition is susceptible to adminstration of superoxide dismutase, the method comprising topically administering to the human body or part thereof a pharmaceutical composition comprising a low-fat or fat free carrier together with ...

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  • (PDF) Oxidative stress in hypercholesterolemia and its ...

    The carbonylation of serum proteins was determined by the Levine method with modifications [31]. Whole blood catalase activity was determined by the method of Aebi [32] by measuring the rate of decomposition of H 2 O 2 at 240 nm. Whole blood superoxide dismutase activity was measured as described by McCord and Fridovich [33].

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  • Frontiers

    Diabetic cardiomyopathy (DCM) is a serious complication of diabetes mellitus (DM). One of the hallmarks of the DCM is enhanced oxidative stress in myocardium. The aim of this study was to research the underlying mechanisms involved in the effects of dapagliflozin (Dap) on myocardial oxidative stress both in streptozotocin-induced DCM rats and rat embryonic cardiac myoblasts H9C2 cells exposed ...

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  • Antioxidative factors in milk - Cambridge

    Antioxidative factors in milk Helena Lindmark-Ma˚nsson1,2* and B. A˚ kesson2 1Swedish Dairy Association, Scheeleva¨gen 18, SE-223 63 Lund, Sweden 2Division of Biomedical Nutrition, Center for Chemistry and Chemical Engineering, Lund University, SE-221 00 Lund, Sweden Lipid auto-oxidation in milk is affected by a complex interplay of pro- and antioxidants.

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  • Glucose-sensing microRNA-21 disrupts ROS homeostasis

    2018-7-23u2002·u2002Antioxidant enzymes play a fundamental role in counteracting oxidative stress induced by high glucose. Although mitochondrial superoxide dismutase (SOD2) is the principal defence against the toxicity of superoxide anions, the mechanism of its inactivation in diabetic subjects is still poorly understood. Recently, microRNA-21 has been associated with diabetes, although its function remains …

    Get Price
  • BLACKMORES Vitamins & Supplements - Australia's #1 ...

    Manganese is an essential trace mineral that is a co-factor in many of the body's enzymes, including superoxide dismutase. Manganese can be found in hazelnuts, blackberries, pineapple, lentils, beans and whole grains. Zinc amino acid chelate (zinc 15 mg): 75 mg. Zinc is an essential trace element that plays a role in every living cell in the body.

    Get Price
  • CSIRO PUBLISHING

    Reproduction, Fertility and Development is an international journal publishing original research, review and comment in the fields of reproduction and developmental biology in …

    Get Price
  • Identification and Molecular Characterization of ...

    2019-9-16u2002·u2002Philasterides dicentrarchi is a free-living microaerophilic scuticociliate that can become a facultative parasite and cause a serious parasitic disease in farmed fish. Both the free-living and ...

    Get Price
  • Frontiers

    2019-4-16u2002·u2002The current study investigated how bovine milk extracellular vesicles (EVs) affected rotarod performance and biomarkers of skeletal muscle physiology in young, growing rats. Twenty-eight-day Fisher 344 rats were provided an AIN-93G-based diet for 4 weeks that either remained unadulterated [EVs and RNA-sufficient (ERS; n = 12)] or was sonicated [EVs and RNA-depleted (ERD; n = 12)].

    Get Price
  • Biochemical and Mineral Alterations of Milk Chemistry in ...

    2017-6-7u2002·u2002The values for fat were lower in mastitic animals as compared to the healthy control group. Our findings are in agreement with Holdaway (1990), Auldist (1995) and Auldist and Hubble (1998). Holdaway (1990) stated that in clinical mastitis the fat content decreases because of …

    Get Price
  • Glucose-sensing microRNA-21 disrupts ROS homeostasis

    2018-7-23u2002·u2002Antioxidant enzymes play a fundamental role in counteracting oxidative stress induced by high glucose. Although mitochondrial superoxide dismutase (SOD2) is the principal defence against the toxicity of superoxide anions, the mechanism of its inactivation in diabetic subjects is still poorly understood. Recently, microRNA-21 has been associated with diabetes, although its function remains …

    Get Price
  • CSIRO PUBLISHING

    Reproduction, Fertility and Development is an international journal publishing original research, review and comment in the fields of reproduction and developmental biology in …

    Get Price
  • Acetyl-L-Carnitine Supplementation Differently Influences ...

    Fat content was determined by the method of Folch et al., and converted to energy as fat by using the coefficient of 39.2 kJ/g. Protein content was determined as described by Brooks et al., and converted to energy as protein by using the value of 23.5 kJ/g. Free triiodothyronine and leptin serum concentrations.

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  • Differences in the Expression of Heat-Shock Proteins and ...

    1995-11-1u2002·u2002It has previously been observed that the insulin-producing cells of human pancreatic islets are more resistant to alloxan-, streptozotocin-, nitroprusside-, or cytokine-induced injury than those of mouse and rat islets. Human pancreatic islets were obtained from heart-beating organ donors. The expression of the stress proteins heat shock protein 70 (hsp70) and heme oxygenase and the anti ...

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  • Research Article ACE Reduces Metabolic Abnormalities in

    2019-7-31u2002·u2002Research Article ACE Reduces Metabolic Abnormalities in a High-Fat Diet Mouse Model Seong-JongLee, 1 Jong-MinHan, 2 Jin-SeokLee, 2 Chang-GueSon, 2 Hwi-JinIm, 2 Hyun-KyungJo, 1 Ho-RyongYoo, 1 Yoon-SikKim, 1 andIn-ChanSeol 1 Internal Medicine of Cardiac Vascular System, Daejeon Oriental Hospital of Daejeon University,- Daedeok-daero,

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  • Short-Term Diet and Moderate Exercise in Young

    Abstract. The present study was designed to evaluate the effects of diet lifestyle on extending lifespan and reducing liver cancer risk. Young overweight men, without metabolic syndrome, were placed in a 3-week residential program on a low-fat diet and moderate aerobic exercise.In each subject, pre- and postintervention fasting blood were collected for evaluating levels of serum lipids, and ...

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  • Health benefits of milk and functional dairy products

    2017-1-26u2002·u2002blood pressure,5,6 and decreased risk of stroke, colon cancer7–9 and osteoporosis.10,11 There is a wide range of functional foods that were developed recently and many of them are being produced in all over the world including probiotic, prebiotic and synbiotic foods as well as foods enriched with fat-reduced, salt-reduced foods or sugar-reduced

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  • Further Characterization of Bovine Superoxide Dismutase ...

    1971-5-10u2002·u2002The superoxide dismutase from bovine erythrocytes and from bovine heart were accordingly analyzed for zinc by the dithizone method (14). The erythrocyte enzyme was found to contain 1.71 and the heart enzyme 1.76 moles of zinc per 32,600 g of enzyme.

    Get Price
  • Variation of Superoxide Dismutase in Bovine Milk ...

    1978-8-1u2002·u2002Variation in the enzyme (superoxide dismutase) concentration may have a minor effect on the oxidative stability of individual cow's milk. Milk from 11 Holsteins and 11 Jerseys were analyzed for 17 wk for superoxide dismutase, xanthine oxidase, oxidized lipids as determined by thiobarbituric acid values, milk produced, and fat content.

    Get Price
  • SOD B®

    SOD B ® is a dried melon juice concentrate naturally rich in SuperOxide Dismutase (SOD), obtained from a non-GMO proprietary variety of Cantaloup melon. SOD B ® is the unique source of bioactive melon SOD worldwide. SOD represents 85 to 90% of the total antioxidant capacity of SOD B ®. As a concentrate, SOD B ® is not pure SOD and also contains secondary antioxidants such as glutathione ...

    Get Price
  • 6647 - Gene ResultSOD1 superoxide dismutase 1 [ (human)]

    2021-10-31u2002·u2002The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

    Get Price
  • Superoxide Dismutase - an overview

    Superoxide dismutase (SOD) is a crucial scavenging enzyme that oxidatively phosphorylates superoxide anions into hydrogen peroxides. 16 It plays an essential role in protecting cells against lipid peroxidation. 28 The antioxidant SOD is highly sensitive to any slight change in the redox state of the cell and its level rises up in response to ...

    Get Price
  • Superoxide Dismutases: Role in Redox Signaling, Vascular ...

    2011-9-15u2002·u2002Generation and metabolism of reactive oxygen species (ROS). Superoxide (O 2 •−) is produced by NADPH oxidase, xanthine oxidase, nitric oxide synthase (NOS), lipoxygenase, and mitochondrial enzymes.Superoxide is converted by superoxide dismutase (SOD) to H 2 O 2, which, in turn, is reduced to water by catalase, glutathione peroxidases (GPx), and peroxiredoxins (Prx).

    Get Price
  • (PDF) Blood antioxidant profile and lipid peroxides in ...

    and SCC recorded in milk of mastitic cows were 3.67 revealed a significant decrease in GSH concentration. 5. ±0.13 and 83.12±1.17 x 10 per ml respectively. Out of in mastitic cows which may be ...

    Get Price
  • Activity, thermostability and isozymes of superoxide ...

    2012-5-1u2002·u2002Activity, thermostability and isozymes of superoxide dismutase (SOD) of 17 edible mushrooms from China were investigated in this study. The results indicated that most of these mushrooms have high SOD activities, especially Pleurotus citrinopileatus, Agaricus bisporus, Pleurotus ostreatus, Volvariella volvacea and Agrocybe aegerita, which contained SOD activities of higher than 1000 units per ...

    Get Price
  • Nitric oxide, superoxide, and peroxynitrite: the good, the ...

    2020-3-5u2002·u2002Nitric oxide is removed within seconds in vivo by diffusion over 100 microns through tissues to enter red blood cells and react with oxyhemoglobin. The direct toxicity of nitric oxide is modest but is greatly enhanced by reacting with superoxide to form peroxynitrite (ONOO-).

    Get Price
  • Bovine serum cholesterol and triglyceride concentrations ...

    Download Table Bovine serum cholesterol and triglyceride concentrations in 2 production cycles. Values are mean ± SD, mmol/l. from publication: Serum paraoxonase 1 (PON1) activity and lipid ...

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